Breathe Clean Air Air and Breathing

Lung Diseases

Air Quality

Some Topics

  • Short of Breath (Dyspnea)

    Dyspnea means difficulty breathing or shortness of breath. There is a subjective component. The dyspnea patient is distressed by sensations of difficulty and limited breathing ability. The respiratory system is designed to maintain adequate oxygenation and acid-base status by adjusting the arterial tension of carbon dioxide [PaCO2] to maintain normal pH. Derangements in oxygenation as well as acidemia lead to breathing discomfort.

    Dyspnea may be caused by inadequate delivery of oxygen to, or utilization by muscles. Persona et al summarized the problem: ”Shortness of breath, or dyspnea, an uncomfortable subjective breathing sensation that is distressful or unpleasant in nature, causes anxiety because the shortness of breath feels out of proportion to the degree of effort exerted. By contrast, an exercising athlete, for example, will not complain of dyspnea because a degree of respiratory difficulty is expected. Dyspnea prevalence increases with age from as low as 2.4% in the population aged 18 years and older to 32% in the population aged 70 years and older.”

    The rate and depth of breathing is regulated by a host of sensors and brain responses. The sympathetic nervous system is the master controller that increases heart and breathing rates when activated. Sympathetic dyspnea is often described as an anxiety attack. Breathing is regulated by signals from neural receptors in the lungs, large and small airways, respiratory muscles and chest wall. Arterial sensors are found in the carotid and aortic bodies and central chemoreceptors respond to the partial pressure of oxygen (PO2), partial pressure of carbon dioxide (PCO2) and pH of the blood and cerebrospinal fluid. The diagnosis of dyspnea begins with assessing lung and heart function. Cardiac causes of dyspnea include congestive heart failure, coronary artery disease, recent or remote myocardial infarction, cardiomyopathy, valvular dysfunction, left ventricular hypertrophy with resultant diastolic dysfunction, asymmetric septal hypertrophy, pericarditis and arrhythmias. Pulmonary causes include obstructive and restrictive processes. The most common obstructive causes are chronic obstructive pulmonary disease (COPD) and asthma. Restrictive lung problems include extrapulmonary causes such as obesity, spine or chest wall deformities, and intrinsic pulmonary pathology such as interstitial fibrosis, pneumoconiosis, granulomatous disease or collagen vascular disease.

    Other body systems may be the cause: metabolic conditions such as anemia, diabetic ketoacidosis and other, less common causes of metabolic acidosis, pain in the chest wall or elsewhere in the body, and neuromuscular disorders such as multiple sclerosis and muscular dystrophy. Nasal obstruction due to allergy, polyps or septal deviation, enlarged tonsils and supraglottic or subglottic airway stricture may contribute to or cause dyspnea.

    Allergic reactions are created by the release of cytokines, molecular signals that effect breathing. This is most evident during asthma attacks caused by food, drugs and airborne exposure to antigens. The cytokines may cause swelling at all levels of the respiratory tract, obstructing airflow. Systemically released cytokines may activate receptors that control breathing causing dyspnea. The anaphylaxis victim may be hyperventilating as his or her body release adrenalin to counteract the decreasing blood pressure associated with the allergic reaction.(Gene R. Pesola et al. Screening for Shortness of Breath: Stretching the Screening Paradigm to Tertiary Prevention. Am J Public Health. 2017;107(3):386-388.)

  • Discussions of Environmental Science and Human Ecology were developed by Environmed Research Inc. Sechelt, B.C. Canada. Online Topics were developed from two books,
    Air and Breathing
  • The Environment
  • Air and Breathing helps you understand breathing, respiratory diseases, air quality issues, airborne infections and other causes of breathing disorders. You will find detailed information about the respiratory tract, atmosphere, air pollution, airborne infection, air quality allergy, lung diseases and airborne hazards at home.
    2018 edition 106 pages.
    Air and Breathing Print Edition for Download.

    The Environment

    In the book, The Environment, you will find detailed information about the weather, climate change, soils, forests, energy sources, oceans, the atmosphere, air pollution, climate change, air quality and the politics of the environment. The Environment is available as a Printed book or as an eBook Edition for download.

    Download The Environment as an eBook

    The Author Stephen J. Gislason MD

    Food Causes

    Not all respiratory diseases are caused by airborne pathogens. If asthma, bronchitis and/or nose sinus congestion is chronic or attacks occur frequently in all seasons and are not related to airborne exposure, then consider delayed pattern food allergy as the cause and do diet revision using the Alpha Nutrition Program.

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