Breathe Clean Air Air, Breathing


Environment

Some Topics

 

YINYANG

Sarcoidosis

Sarcoidosis is a multisystem immune-mediated disease. Airborne sources of antigens interact with immune defenses to create the granulomatous immune response in tissues. Granulomas are one form of delayed hypersensitivity reactions in tissues that take weeks or months to form and leave permanent scars. Some chronic infections such as tuberculosis and fungal infections produce granulomas. Sarcoid granulomas appear in the lungs and the lymph nodes that receive antigens from the lungs. Granulomas also appear in the skin and other organs.

Occupational clusters have been reported in health-care workers, US Navy enlistees, teachers, automobile manufacturers, retail industry workers and firefighters. Granulomatous diseases have been associated with exposures to organic dusts, metals, molds, chemical dust, silica, wood dust, and smoke. Izbicki et al followed 26 fire fighters who developed sarcoidosis after exposure to World Trade Center dust during the collapse and rescue/recovery efforts. A large number of exposed citizens developed upper respiratory symptoms, especially chronic cough and increased asthma attacks from inflammation in the upper and lower respiratory tracts but only a small number developed granulomatous disease.

More than 400 substances were found in samples of WTC dust in four main categories: (1) particulate matter (calcium carbonate and silica) and fibers (chrysotile asbestos, fibrous glass, gypsum); (2) organic chemical pollutants, including polycyclic aromatic hydrocarbons, other hydrocarbons (naphthalene, fluorine, polychlorinated biphenyl, dibenzo-p-dioxins, and diphenyl ethers), benzene, and freon; (3) gases, such as carbon monoxide, hydrogen sulfide, combustion byproducts from WTC fires that burned until mid-December 2001, and diesel exhaust fumes from the vehicles/machinery employed during the rescue recovery effort; and (4) heavy metals. Some of these substances had already been associated with granuloma formation.

Gabriel Izbicki, Robert Chavko, Gisela I. Banauch; et al World Trade Center "Sarcoid-Like" Granulomatous Pulmonary Disease in New York City Fire Department Rescue Workers. CHEST 2007;131(5):1414-1423.


  • Discussions of Environmental Science and Human Ecology were developed by Environmed Research Inc. Sechelt, B.C. Canada. Online Topics were developed from the book, Air and Breathing. This book helps you understand air quality issues, normal breathing and the causes of breathing disorders. You will find detailed information about the atmosphere, air pollution, climate change, airborne infection, air quality and airborne hazards at home. Air and Breathing is available as a Printed book or as an eBook Edition for Download

    Download eBook

    The Author Stephen J. Gislason MD.

    Not all respiratory diseases are caused by airborne pathogens. If asthma, bronchitis and/or nose sinus congestion is chronic or attacks occur frequently in all seasons and are not related to airborne exposure, then consider delayed pattern food allergy as the cause and do diet revision using the Alpha Nutrition Program.


    Book Orders

    Click Add to Cart buttons to begin an order for mail delivery (US and Canada). All books can be downloaded as PDF files. Click the Download buttons to order eBooks for download. Pay by Pay Pal for immediate download. Click the book titles (center column) to read topics from each book.

    Print Books Read Topics Download
    Alpha Nutrition Program
    Aching and Fatigue
    Air and Breathing
      Alpha Nutrition Cooking
    Alcohol Problems 
    Gluten Problems 
    Managing Diabetes 2
      Eating and Weight
    Skin Disease
    Feeding Children
      Human Brain
    Food Allergy
    Digestive Disorders
      Food Choices
      Heart & Arterial Disease
      Immunology Notes
    Inflammatory Arthritis
    Nutrition Notes

    Google Search Alpha Online

     
    Alpha Online

    alpha online

    Alpha Online is a Web Site developed by Environmed Research Inc. Sechelt, B.C., Canada. Online Since 1995. Orders for printed books, eBooks and nutrient formulas are placed at Alpha Online. Alpha Nutrition is a registered trademark of Environmed Research Inc.