The prevalence of celiac disease in the general population was believed to be
1 in 300, but recent evidence suggests that there are more undiagnosed than
diagnosed cases. A revised estimate of the prevalence in the general population
may be greater than 1%. The prevalence of CD among first-degree relatives of
people who are diagnosed with CD is as high as 15%. In families with sibling
pairs affected by CD, the prevalence of CD is 21.3% in siblings, 14.7% in
offspring, 17.2% in first-degree relatives, 19.5% in second-degree relatives,
and 17.8% in all relatives.
Immune responses to gluten, the proteins found in cereal grains are a common
cause of disease. The gastrointestinal tract is the primary target organ;
however systemic disease is an important consequence of cereal grain ingestion
in many patients. We think that the people diagnosed with celiac disease are a
sub-population of a much larger group with gluten allergy. Latent disease may
manifest as irritable bowel syndrome, sometimes with iron deficiency anemia, but
little or no diarrhea. Celiac disease is associated with a variety of autoimmune
disorders, carcinomas of the gastrointestinal tract and lymphomas.
Gluten-sensitive patients have not been diagnosed.
The prevalence of all forms of gluten allergy may be closer to 20% in a
symptomatic population. Most gluten-sensitive patients have not been
diagnosed. We argue that any person with celiac-like symptoms, gastrointestinal
symptoms, and/or autoimmune disease should do diet revision right away and not
worry about an exact diagnosis.
Catassi et al suggested: Many cases of celiac disease are currently
undiagnosed. We carried out a pilot study on screening for celiac disease in a
school population. The ratio of known to undiagnosed cases was 1 to 6.4. This
high prevalence of undiagnosed celiac disease raises a number of problems that
require further evaluation. Corazza and Gasbarrini suggested: Since it has been demonstrated that a
strict gluten-free diet is protective against the complications of adult celiac
disease, it is important that even subclinical and silent forms are diagnosed
and treated as early as possible."
Ciacci et al suggested that celiac disease may present in various forms. Their
study showed that the disease is more frequent in women, more severe and
develops more rapidly. They stated: "The data also suggest the need to look for celiac disease in patients with
unexplained anemia. Except for asthenia, all signs and symptoms were more
frequent in women than in men. Anemia was the commonest finding in women and was
40% more frequent in women than in men. Dyspepsia was twice as frequent in women
as in men. Genital disorders were reported by 44% of women and by no men. Recent
weight loss or low body mass index was the commonest finding in men. About 60%
of men and women reported diarrhea; among patients without diarrhea, the
prevalence of anemia differed between sexes, occurring in about 80% of women."
Biopsy Not Required
Our argument is that gluten-caused disease and the diagnosis of gluten
allergy should not depend on intestinal biopsy. The biopsy reveals only one
pathological manifestation of gluten allergy. We recommend gluten elimination in
all digestive tract disorders and in all the conditions that a commonly related
to celiac disease. Our theory is that gluten proteins produce a number of
diseases that overlap and are only occasionally manifest as well-defined,
The diagnosis of celiac disease is, therefore, an arbitrary separation of one
small subgroup within a much larger group that suffers disease when they eat
gluten. Our assumption is that if you look at symptomatic populations with
gastrointestinal symptoms and/or autoimmune disease, then the incidence of
gluten sensitivity will be higher than expected. Since a strict gluten-free diet
is protective against the consequences of gluten allergy, it is important that
undiagnosed forms of celiac disease and non-celiac "gluten allergy" are treated
with diet revision.
Troncone et al * stated: "Gluten-sensitive enteropathy is induced by dietary
wheat gliadin and related proteins in genetically susceptible individuals. Most
evidence suggests an immunologically mediated injury triggered by gluten … it is
now becoming clear that a greater proportion of individuals has clinically
silent disease, and probably many others have a minor form of the enteropathy.
In most countries, the clinical presentation has changed over the past few years
coming closer to the adult type of the disease, and the age of onset of symptoms
is shifting upward.
Recommendations: The Alpha Nutrition Program is gluten-free and is
recommended as the diet revision strategy for anyone with diagnosed celiac
disease, or any person with symptoms suggestive of gluten allergy. The
diet revision program is explained in enough detail in the Alpha Nutrition
Program Manual that an intelligent, well-motivated person can follow the
steps outlined. You can order the manual and the Book of Celiac togetherin the
starter pack. Alpha Nutrient Formulas are gluten free. Please note that
maltodextrin, used in Alpha ENF and Alpha PMX, does not contain gluten and is
not related to barley-derived malt.
Learn more About Gluten Rescue Starter Pack
Hear About Celiac Disease and Gluten Allergy Prevalence
The book, Gluten Problems and Solutions provides both an
introduction and also advanced explanations of the immunological basis of gluten
induced diseases. The Alpha Nutrition Program is designed to solve the heath problems
related to gluten which we consider to be both common and serious. The
author is Stephen Gislason MD.
Gluten Free: The exclusion of wheat, rye, barley are the
initial steps when gluten allergy is suspected. Gluten elimination should be
part of a more comprehensive diet revision plan, preferably in the form outlined
in the Alpha Nutrition Program. The Program is gluten-free and is recommended as
the best diet revision strategy for anyone with diagnosed celiac disease, or any
person with symptoms suggestive of gluten allergy. Learn more about the Alpha Nutrition ProgramGluten free recipes are found in the book,
Cooking and Recipes.
A good way to start your recovery is to Order a Gluten Rescue Starter Packwhich includes 2 books and Alpha
ENF. If you are not ready for the starter pack, order books and formulas separately.
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