femme Neuroscience

Some Topics

  • Two Hands, Two Hemispheres - Cerebral Cortex

    One advantage of the popular right and left-brain speculations is that most people know they have two cerebral hemispheres. The left hemisphere controls the right half of the body and visa versa. The crossed innervation of the body is one of those curious facts that has no particular explanation. It just happens to be the case. Damage or disease in the left hemisphere shows up in the right side of the body and visa versa. The left hemisphere tends to be dominant in terms of hand use and language storage in about 92% of humans. Language is the most important lateralization of function that is linked to hand dominance. You determine dominance by watching which hand holds a pen and does more of the fine motor skills. The dominant side of the body also tends to be larger than the non-dominant side. About 4% of humans have right hemisphere dominance and another 4% are in the middle with more or less symmetrical hemispheric function.

    The human hand is remarkably adaptable. The brain systems that control hand movements are more remarkable. Human hands hold tools, gesture, express feelings and meanings. Two hands work together in most tasks. This means that the two hemispheres work together by sending signals back and forth through a massive bundle of wires, the corpus callosum. In normal people, the left and right hemispheres form integrated operating systems that are often tightly coordinated as in walking, running, and tool use.
    Clumsy people are less coordinated and some have distinct difficulty achieving left and right cooperation. The dominant hand leads the non dominant hand by 15 to 30 milliseconds when coordinated movements are performed. This suggests that the left hemisphere initiates the movement and sends signals to the right.

    This asymmetric activation of the hemispheres may come from below the cerebral cortex (from the thalamus, for example) and may have implications about how all volitional activity is organized. A popular notion, that the dominant left hemisphere is “analytic” and the right hemisphere is “synthetic or artistic,” makes little sense and is not a good way to try to understand how the human brain works. A better understanding is based on understanding left hemisphere language dominance; about 92% of humans speak to themselves and to others from the left side of the brain.

    Split Brains

    Sperry and other surgeons gave impetus to right-left theories by cutting the main interhemispheric connector, the corpus callosum in patients with epilepsy. Studies of cognitive function revealed some interesting features of these Split-brain" ” patients who could not send signals back and forth between their hemispheres. These were distinctly abnormal people and their peculiarities did not reveal how normal people work. As one would expect, the split-brain patients had disconnected cognitive functions because their hemispheres could not share information. In contrived experiments, information could be supplied to only one hemisphere and would not be available to the other. Each hemisphere revealed a separate consciousness in terms of responses to stimuli and reportable contents. Usually, only the left hemisphere could speak and could only report on information received on the left. The right hemisphere could not speak, but communicated with nonverbal vocalizations and in other ways.

    Coordination of left and right

    A normal person would have constant traffic of information between the two hemispheres and would integrate rather than separate lateralized functions. The coordination of left and right hand and arm movements is important to human survival. Both hands are needed to perform most tasks and although the hands may do different tasks, both hands cooperate and work toward the same goal. The right-left linkage shows up clearly whenever you try to perform distinctly different tasks with each hand. Even with sustained practice, the two hands want to do similar things or perform linked movements as you do when you play the bongo drums or knit sweaters. I spent years, for example, trying to achieve right and left hand separation as I played the piano. I was inspired by the great Canadian pianist, Glenn Gould , who achieved, while playing piano pieces by J.S. Bach, remarkable independence of his left and right hands. In fact, he seemed to achieve independence for each finger of each hand. If you listen closely, you can hear him play individual notes with individual attention. Gould played Bach and Bach’s preludes and fugues that were based on four voices that sang through the fingers of both hands. An alto voice could start in the left hand, pass to the right and back to the left. Of course, Gould was a musical genius with a prodigious memory. He learned musical scores away from the piano; playing the piece followed memorizing and rehearsing it in his mind. Donchin et al offered a description of hand coupling: “…movements of the arms are naturally coupled. For instance, certain modes of temporal coupling are more natural for the system than others. In-phase (clapping) and anti-phase (walking) rhythms can be maintained at higher frequencies than other phase relationships; further, in-phase rhythms are more stable than anti-phase rhythms. Spatial coupling of movements also exists: subjects easily produce circles or lines with both hands simultaneously, but when they draw lines with one hand and circles with the other, they make ovals with both hands… Franz and Ramachandran, showed that amputees with phantom limb effects are susceptible to spatial coupling even though the amputated limb cannot move, and there are similar results in normals who are moving one arm and imagining movement of the other. A difference between mechanisms underlying temporal and spatial bimanual control makes a variety of neurophysiological explorations possible. Central pattern generators (CPGs) play a role in the coordination of rhythmic, bilateral movements and have been found in the spinal cord. Since CPGs are affected by cortical and subcortical efferents, the cortex may modulate temporal coupling through them. For instance, it may control the resonant frequencies of the CPG or modulate limb activation at different phases of the cycle…This is consistent with the inter-hand time lag: hemispheric dominance might lateralize CPG activation, and lateralized activation could cause asynchrony in the movements. “

    Helen Mesaros. Psychobiography of a virtuoso. http://www.gould.nlc-bnc.ca/docs/epsycho.htm:) (Donchin, S. Cardoso de Oliveira, E. Vaadia Who Tells One Hand What the Other Is Doing: The Neurophysiology of Bimanual Movements Neuron, Vol. 23, 15–18, May, 1999


  • Neuroscience Notes

  • This book places the human brain at the center of the universe. Since the brain is the organ of the mind, consciousness and all knowledge is contained within the brain. Everyone needs to know something about neuroscience. The brain has become a popular topic in all media, but confusions arise when the brain becomes an abstract fantasy in the minds of journalists and product promoters. While it is true that brain is the organ of the mind, our language makes it difficult to speak correctly at different levels of meaning. Neuroscience notes will give the intelligent reader and understanding of how the brain actually works.

  • Neuroscience Notes is part of the Persona Digital Psychology and Philosophy Series of related books. The closely related volumes are the Human Brain, Language and Thinking, Emotions and Feelings, Intelligence and Learning. Neuroscience notes is available as eBook download from Alpha Online.
  • The author is Stephen Gislason MD The latest date of publication is 2018. 306 Pages 

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